LEPR, leptin receptor, 3953

N. diseases: 416; N. variants: 57
Disease: Lobar Pneumonia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032300
Disease: Lobar Pneumonia
Lobar Pneumonia 		0.010 Biomarker disease BEFREE Since leptin deficiency is associated with obesity and other metabolic abnormalities, we generated mice that lack the leptin receptor (LepRb) in cells of the myeloid linage (LysM-LepRb-KO) to evaluate its impact in lean metabolically normal mice in a murine model of pneumococcal pneumonia. 29565180 2018