LIF, LIF interleukin 6 family cytokine, 3976

N. diseases: 236; N. variants: 4
Disease: Cerebrovascular accident ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.250 Biomarker group BEFREE Previously, this lab showed that leukemia inhibitory factor (LIF) promoted recovery after stroke through antioxidant enzyme upregulation. 30445025 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.250 AlteredExpression group BEFREE Neuroprotective activity of leukemia inhibitory factor is relayed through myeloid zinc finger-1 in a rat model of stroke. 30612292 2019
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.250 Biomarker group BEFREE The goal of this study was to determine whether LIF protects neurons during stroke by upregulating superoxide dismutase 3 (SOD3). 26746670 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.250 Biomarker group BEFREE AD, Alzheimer's disease; FAST, Functional Assessment Staging; 2D-DIGE, two-dimensional differential gel electrophoresis; MALDI-TOF/TOF/MS, matrix-assisted laser desorption ionization time-of-flight tandem mass spectrometry; CSF, cerebrospinal fluid; Aβ, amyloid beta; MMSE, Mini Mental State Examination; MRI, magnetic resonance imaging; NINCDS-ADRDA, National Institute for Neurological Diseases and Stroke/Alzheimer's Disease and Related Disorders Association; CHAPS, 3-((3-cholamidopropyl) dimethylammonio)-1-propanesulfonate; DTT, dithiothreitol; SDS-PAGE, SDS-polyacrylamide gel electrophoresis; DIA, differential in-gel analysis; BVA, biological variation analysis; CBB, Coomassie brilliant blue; 2DE, two-dimensional gel electrophoresis; TFA, trifluoroacetic acid; ACTH, adrenocorticotropic hormone; Apo A-1, apolipoprotein A-1; AHSG, alpha-2-HS-glycoprotein; Apo A-4, apolipoprotein A-4; MCI, mild cognitive impairment. 28107809 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.250 Biomarker group RGD Leukaemia inhibitory factor is over-expressed by ischaemic brain tissue concomitant with reduced plasma expression following acute stroke. 18042242 2008
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.250 AlteredExpression group LHGDN Leukaemia inhibitory factor is over-expressed by ischaemic brain tissue concomitant with reduced plasma expression following acute stroke. 18042242 2008