LIMK1, LIM domain kinase 1, 3984

N. diseases: 271; N. variants: 3
Disease: Non-Small Cell Lung Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 Biomarker disease BEFREE LIMK1 was further identified as a direct target of miR‑138 in NSCLC H460 cells. 27665963 2016
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 PosttranslationalModification disease BEFREE Knockdown of PAK4 in NSCLC cell lines led to reduce the phosphorylation of LIMK1, which resulted in decrease of the cell migration and invasion. 25975262 2015
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 Biomarker disease BEFREE Together, our results highlight the significance of miR-143 and Limk1 in the development and progression of NSCLC. 25003638 2014
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 Biomarker disease BEFREE Finally, LIMK1 was found to be negatively correlated with miR-27b in NSCLC patients. 24390089 2014
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.050 AlteredExpression disease BEFREE In addition, overexpression of LIMK1 was also associated with high TNM stage and lymph node metastasis in NSCLC patients. 24063279 2013