LOX, lysyl oxidase, 4015

N. diseases: 328; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm
0.050 GeneticVariation disease BEFREE In this study, we investigated the association between LOX gene polymorphisms and intracranial aneurysm (IA) formation in a homogeneous Korean population. 28792146 2017
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm
0.050 GeneticVariation disease BEFREE This study also could not observe any significant role of LOX polymorphisms in influencing IA either directly or indirectly through its confounding factors such as hypertension and gender in South Indian population. 24065528 2013
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm
0.050 Biomarker disease BEFREE Systematic screening of lysyl oxidase-like (LOXL) family genes demonstrates that LOXL2 is a susceptibility gene to intracranial aneurysms. 17287949 2007
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm
0.050 GeneticVariation disease BEFREE Genetic variants in the lysyl oxidase gene do not appear to be a major factor in the etiology of intracranial aneurysms in Central Europe. 15273433 2004
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm
0.050 Biomarker disease BEFREE No associations of FBN2 and LOX with IA were detected in the present study. 12750963 2003