LOXL2, lysyl oxidase like 2, 4017

N. diseases: 149; N. variants: 7
Disease: Microaneurysm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0333101
Disease: Microaneurysm
Microaneurysm 		0.010 Biomarker disease BEFREE Thickening of the basement membrane in small microaneurysms by accumulation of matrix proteins probably produced by recruited pericytes, together with the appearance of crosslinked collagen III fibrils probably due to the action of LOXL2 and LOXL4, could be considered as compensatory mechanisms to strengthen the vascular wall in the early phase of microaneurysm formation. 28196225 2017