LPA, lipoprotein(a), 4018

N. diseases: 340; N. variants: 49
Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.050 Biomarker disease BEFREE Lysophosphatidic acid (LPA) is a potent inducer of colon cancer and LPA receptor type 2 (LPA(2)) is overexpressed in colon tumors. 21134377 2011
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.050 AlteredExpression disease BEFREE The S1P and LPA receptors were expressed to a variable degree on all tumor cell lines tested (with exception of colon cancer SW480). 20480410 2010
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.050 AlteredExpression disease BEFREE Among the four members of the LPA receptor family, LPA(2) has been shown to be overexpressed in colon cancer suggesting that the signaling by LPA(2) may potentiate growth and survival of tumor cells. 17544220 2007
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.050 AlteredExpression disease BEFREE Expression of human apolipoprotein(a) kringles in colon cancer cells suppresses angiogenesis-dependent tumor growth and peritoneal dissemination. 15517541 2005
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.050 AlteredExpression disease BEFREE No Apo A-I mRNA was detected in the healthy donors and in the patients without colon cancer. 9683776 1998