LPA, lipoprotein(a), 4018

N. diseases: 340; N. variants: 49
Disease: Intracranial Aneurysm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.040 Biomarker disease BEFREE The 2 LPA variants were combined and examined as LPA scores for the association with ischemic stroke (and TOAST [Trial of Org 10172 in Acute Stroke Treatment] subtypes) (effective sample size [n(e)] = 9,396); peripheral arterial disease (n(e) = 5,215); abdominal aortic aneurysm (n(e) = 4,572); venous thromboembolism (n(e) = 4,607); intracranial aneurysm (n(e) = 1,328); CAD (n(e) = 12,716), carotid intima-media thickness (n = 3,714), and angiographic CAD severity (n = 5,588). 22898070 2012
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.040 GeneticVariation disease BEFREE We performed a comparative analysis of size polymorphisms at two loci (kringle 4 [K4] and TTTTA pentanucleotide [PN] repeats) within the apolipoprotein(a) gene on Chromosome 6q26-27 among patients with sporadic IAs (n = 50), members of three IA families (n = 50), and control subjects (n = 50). 11440434 2001
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.040 AlteredExpression disease BEFREE Risk factors for general atherosclerosis (hypertension, smoking, hypercholesterolemia, high levels of blood triglycerides, lipoprotein a, and apoprotein A1) and use of alcohol do not increase the risk of intracranial aneurysms significantly in these relatives. 10496256 1999
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.040 Biomarker disease BEFREE Elevated serum lipoprotein (a) [Lp(a)] level, an independent risk factor for atherogenesis, has been demonstrated in sporadic IA disease (1). 9149281 1997