LPA, lipoprotein(a), 4018

N. diseases: 340; N. variants: 49
Disease: Calcification of mitral valve ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919718
Disease: Calcification of mitral valve
Calcification of mitral valve 		0.010 GeneticVariation disease BEFREE Eight gene polymorphisms were significantly associated with severe bioprosthetic mitral valve calcification and were therefore included into stepwise logistic regression which identified male gender, the T/T genotype of the rs3775073 polymorphism within the TLR6 gene, the C/T genotype of the rs2229238 polymorphism within the IL6R gene, and the A/A genotype of the rs10455872 polymorphism within the LPA gene as independent predictors of severe bioprosthetic mitral valve calcification. 27589735 2016