LPL, lipoprotein lipase, 4023

N. diseases: 290; N. variants: 116
Disease: Insulin resistance syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3714619
Disease: Insulin resistance syndrome
Insulin resistance syndrome 		0.040 Biomarker disease BEFREE Haplotype 2 was identified as a new risk haplotype, suggesting the complex nature of LPL's effect on features of the insulin resistance syndrome. 17032721 2007
CUI: C3714619
Disease: Insulin resistance syndrome
Insulin resistance syndrome 		0.040 GeneticVariation disease BEFREE This haplotype-based genetic analysis provides compelling evidence that variation in the LPL gene plays a role in determining insulin resistance in this ethnic group with a high prevalence of the insulin resistance syndrome. 14693718 2004
CUI: C3714619
Disease: Insulin resistance syndrome
Insulin resistance syndrome 		0.040 Biomarker disease BEFREE This presumed impaired effect of insulin on LPL postprandially could be an important contributor to the atherogenic dyslipidaemia described in insulin resistance syndrome. 11895454 2002
CUI: C3714619
Disease: Insulin resistance syndrome
Insulin resistance syndrome 		0.040 AlteredExpression disease BEFREE This appears to be the first reported genetic association with the insulin-resistance syndrome and may reflect genotype specific differences in the regulation of lipoprotein lipase by insulin. 7905375 1993