LRP4, LDL receptor related protein 4, 4038

N. diseases: 151; N. variants: 23
Disease: Myasthenias ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0947912
Disease: Myasthenias
Myasthenias 		0.020 Biomarker disease BEFREE Our results clearly demonstrate that active immunization of mice with LRP4 proteins causes myasthenia similar to the MG induced by anti-MuSK Abs. 28823823 2017
CUI: C0947912
Disease: Myasthenias
Myasthenias 		0.020 Biomarker disease BEFREE By contrast, mutations in lipoprotein-like receptor 4 (LRP4), a long-time candidate gene for congenital myasthenia, and a novel phenotype of myasthenia with distal weakness and atrophy due to mutations in AGRN have now been described. 25305004 2014