LTA4H, leukotriene A4 hydrolase, 4048

N. diseases: 63; N. variants: 11
Disease: Tuberculosis, Pulmonary ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041327
Disease: Tuberculosis, Pulmonary
Tuberculosis, Pulmonary 		0.030 Biomarker disease BEFREE LTA4H, IL10 and IFNG SNPs showed no associations with pulmonary tuberculosis. 25239251 2015
CUI: C0041327
Disease: Tuberculosis, Pulmonary
Tuberculosis, Pulmonary 		0.030 GeneticVariation disease BEFREE Two single nucleotide polymorphisms in Leukotriene A4 hydrolase (LTA4H) gene were reported to be associated with protection from pulmonary tuberculosis in Vietnamese population. 25257262 2014
CUI: C0041327
Disease: Tuberculosis, Pulmonary
Tuberculosis, Pulmonary 		0.030 GeneticVariation disease BEFREE It also reported that heterozygosity at the two single nucleotide polymorphisms rs1978331 and rs2660898 located in introns of the LTA4H gene, a human homologue of lta4h, is associated with protection from pulmonary tuberculosis. 21112816 2011