LTA4H, leukotriene A4 hydrolase, 4048

N. diseases: 63; N. variants: 11
Disease: Neutrophilia (disorder) ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3665444
Disease: Neutrophilia (disorder)
Neutrophilia (disorder) 		0.010 Biomarker disease BEFREE Components of cigarette smoke can acetylate PGP, yielding a species (AcPGP) that is resistant to LTA4H-mediated degradation and can, thus, support a sustained neutrophilia. 29202450 2017