LTA, lymphotoxin alpha, 4049

N. diseases: 353; N. variants: 26
Disease: Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.080 Biomarker disease BEFREE Lymphotoxin alpha (LTA), a proinflammatory cytokine, plays an important role in promoting atherosclerosis which is an independent risk factor for stroke. 26707826 2016
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.080 Biomarker disease BEFREE We aimed to uncover a potential pathway linking purinergic receptor to LTα-mediated inflammatory processes pivotal to the early stages of atherosclerosis in apolipoprotein E (ApoE(-)(/)(-)) deficient mice. 27355755 2016
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.080 Biomarker disease BEFREE So the purpose of the present study was to investigate the possible involvement of LTA in the pathogenesis of atherosclerosis and MI in Chinese. 19365711 2010
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.080 Biomarker disease BEFREE Lymphotoxin alpha (LTA), one of the tumor necrosis factor family proteins, is an important proinflammatory cytokine and appears to play a putative role in the inflammatory process of atherosclerosis. 18349535 2008
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.080 GeneticVariation disease LHGDN The LTA 252A/G polymorphism is moderately associated with sub-clinical atherosclerosis. 16874159 2006
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.080 Biomarker disease BEFREE The proinflammatory cytokine, tumor necrosis factor beta (TNF-beta), is thought to contribute to the pathogenesis of atherosclerosis. 17194634 2006
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.080 GeneticVariation disease BEFREE The apolipoprotein E and the tumor necrosis factor beta polymorphisms are risk factors for atherosclerosis. 15224026 2004
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.080 GeneticVariation disease BEFREE TNFA and TNFB polymorphisms are unlikely to contribute to progression of atherosclerosis in a way clinically important. 11257271 2001