Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This study focuses on studying the association of inflammatory cytokine polymorphisms like TNF-α -308 (G/A), TNF-β +252 (A/G), IL-6 -174 (G/C) and IL-6 -597 (G/A), and IFN-ɣ +874 (T/A) with coronary artery disease (CAD) among north Indian patients.
|
28739396 |
2017 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Increased risk for CHD was likely to be associated with interaction of IFN-γ with diastolic hypertension, TNF-α with diabetes and BMI, and TNF-β with serum triglyceride and very low density lipoprotein (VLDL) levels.
|
23159874 |
2013 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Haplotype-based association of four lymphotoxin-alpha gene polymorphisms with the risk of coronary artery disease in Han Chinese.
|
21628868 |
2011 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
No population significant differences were detected in LTA genotypes and allele frequencies between coronary heart disease patients or healthy controls (chi(2) = 1.479, P = 0.477 > 0.05).
|
19365711 |
2010 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In present study, the LTA gene and LGALS2-C3279T are not associated with coronary artery disease.
|
19726041 |
2010 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Lymphotoxin alpha LTA+496C allele is a risk factor for periodontitis in patients with coronary artery disease.
|
18384488 |
2008 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Lymphotoxin-alpha gene 252A>G and metabolic syndrome features in Korean men with coronary artery disease.
|
17640627 |
2007 |
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Effects of lymphotoxin-alpha gene and galectin-2 gene polymorphisms on inflammatory biomarkers, cellular adhesion molecules and risk of coronary heart disease.
|
17040205 |
2007 |
Coronary heart disease
|
0.100 |
Biomarker
|
disease |
BEFREE |
Clinical, genetic, and epidemiological studies have linked lymphotoxin-alpha (LTA), a proinflammatory cytokine, to coronary artery disease and myocardial infarction.
|
18190265 |
2007 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms in the gene encoding lymphotoxin-alpha (LTA) on Chromosome 6p21 have been associated with susceptibility to CHD, but results in different studies appear to be conflicting.
|
16839190 |
2006 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Thus, further to the recent finding that LTA gene variation is associated with susceptibility to coronary heart disease, the present study provides evidence of an association between LTA genotype and the extent of coronary atherosclerosis.
|
15973460 |
2005 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A trio family study showing association of the lymphotoxin-alpha N26 (804A) allele with coronary artery disease.
|
15266304 |
2004 |
Coronary heart disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Tumour necrosis factor beta alleles and hyperinsulinaemia in coronary artery disease.
|
9726033 |
1998 |