LY6E, lymphocyte antigen 6 family member E, 4061

N. diseases: 115; N. variants: 0
Disease: Virus Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.040 Biomarker group BEFREE The opposing role of IFN-inducible LY6E in modulating HIV-1 infection highlights the complex roles of ISGs in viral infection and viral pathogenesis. 30674630 2019
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.040 Biomarker group BEFREE In this review, we summarize the current knowledge of LY6E in the context of viral infection, particularly viral entry. 31684192 2019
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.040 Biomarker group BEFREE Cell biological studies found that LY6E forms tubules upon viral infection and bead internalization, and we found that tubule formation was dependent on RNASEK, which is also required for flavivirus internalization, but not transferrin uptake. 29610346 2018
CUI: C0042769
Disease: Virus Diseases
Virus Diseases 		0.040 Biomarker group BEFREE In a screen to identify antiviral ISGs, we unexpectedly found that LY6E, a member of the LY6/uPAR family, enhanced viral infection. 30190477 2018