MIRLET7B, microRNA let-7b, 406884

N. diseases: 186; N. variants: 1
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 AlteredExpression disease BEFREE SNHG16 as the miRNA let-7b-5p sponge facilitates the G2/M and epithelial-mesenchymal transition by regulating CDC25B and HMGA2 expression in hepatocellular carcinoma. 31696971 2020
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE The expressions of NEAT1 and microRNA (miR)-let-7b in HCC tissues and cell lines were quantified by quantitative real-time PCR (qRT-PCR). 31819522 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE These results suggested that appropriate manipulation of let-7b might be a new treatment of human HCC in the future. 30108446 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 AlteredExpression disease BEFREE Let-7b over-expression inhibited the development and growth of implanted HCC tumors in mice by decreasing PLK1 and Survivin expression in the tumors. 29913237 2018
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 Biomarker disease BEFREE As a single marker, α-fetoprotein (AFP) and miR-122 as well as let-7b had the similar performance for differentiate HCC from DN. 26264553 2016
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.060 GeneticVariation disease BEFREE Let-7b binding site polymorphism in the B-cell lymphoma-extra large 3'UTR is associated with fluorouracil resistance of hepatocellular carcinoma. 25333670 2015