MIRLET7E, microRNA let-7e, 406887

N. diseases: 72; N. variants: 3
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 Biomarker disease BEFREE There are compelling evidences indicating that the expression of let-7e is downregulated in various cancers, however, the role of let-7e in colorectal cancer (CRC) and its mechanism has been remained unknown. 31075231 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 Biomarker disease BEFREE Let-7e enhances the radiosensitivity of colorectal cancer cells by directly targeting insulin-like growth factor 1 receptor. 30515804 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 Biomarker disease BEFREE In addition, it was demonstrated that hsa-let-7e-5p stimulated colorectal cancer cell migration <i>in vitro</i>. 29731866 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.040 AlteredExpression disease BEFREE In this study, miR-33a and let-7e levels were confirmed to be significantly down-regulated in CRC samples (n=32) and drug resistant cell line (HCT-8/5-FU) compared with those in the matched adjacent tissues and drug sensitivity cell line (HCT-8). 28751193 2017