MIRLET7E, microRNA let-7e, 406887

N. diseases: 72; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.020 Biomarker disease BEFREE Let-7e suppresses DNA damage repair and sensitizes ovarian cancer to cisplatin through targeting PARP1. 31722968 2020
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.020 Biomarker disease BEFREE Importantly, focal deletion of four let-7 family members was found in three cancer types: medulloblastoma (let-7a-2 and let-7e), breast cancer (let-7a-2), and ovarian cancer (let-7a-3/let-7b). 22970210 2012