MIRLET7G, microRNA let-7g, 406890

N. diseases: 68; N. variants: 0
Disease: Atherosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.050 AlteredExpression disease BEFREE Altogether, sufficient let-7g levels are important to prevent NF-κB over-activation in macrophages and to prevent atherosclerosis. 29254143 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.050 Biomarker disease BEFREE Our previous studies indicate that microRNA let-7g prevents atherosclerosis and improves endothelial functions. 27696675 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.050 Biomarker disease BEFREE Lentivirus carrying the let-7g gene was injected to apolipoprotein E knockout (apoE<sup>-/-</sup> ) mice to confirm let-7g's effect on preventing atherosclerosis. 28699690 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.050 Biomarker disease BEFREE This study suggests that miR-let-7g may be a therapeutic candidate for treating atherosclerosis, and provides novel insight into miRNA-based therapy for this disease. 28535009 2017
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.050 Biomarker disease BEFREE Therefore, miRNA let-7g may play important role in endothelial apoptosis and atherosclerosis. 24252910 2013