LYZ, lysozyme, 4069

N. diseases: 178; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain
0.020 Biomarker phenotype BEFREE Injections of lysozyme in healthy rats increased their mechanical and thermal pain sensitivity. 31391320 2019
CUI: C0030193
Disease: Pain
Pain
0.020 Biomarker phenotype BEFREE Because myeloid cells constitute a major non-neuronal source of BH4 that may contribute to BH4-dependent phenotypes, we studied here the contribution of myeloid-derived BH4 to pain and itch in lysozyme M Cre-mediated GCH1 knockout (LysM-GCH1<sup>-/-</sup> ) and overexpressing mice (LysM-GCH1-HA). 30450838 2019