LYZ, lysozyme, 4069

N. diseases: 178; N. variants: 8
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Engaging Raman microscopy, we made a critical structural analysis of oligomer and other assembly structures of lysozyme obtained from hen egg white and, provided a quantitative estimation of protein secondary structure in different states of its fibrillation. 31820990 2020
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Bacopa monnieri inhibit hen egg white lysozyme fibrillation and help in retaining its activity at acidic condition. 31084353 2020
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Proline functionalized gold nanoparticles modulates lysozyme fibrillation. 30476794 2019
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Effect of Silica Nanoparticles on the Amyloid Fibrillation of Lysozyme. 31459377 2019
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Mono-, di- and tri-carboxylic acids (acetic, lactic, levulinic, malic and citric acids) were used to prepare different DES formulations, which were successfully used on the fibrillation of lysozyme. 29596936 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE The results show that pyrogallol, and 3,4-dihydroxy benzoic acid, each containing the o-dihydroxy moiety exhibited a significant inhibitory effect on lysozyme fibrillation which is further supported by docking studies. 29277421 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Benefiting from the enhanced solubility of 3.32×10<sup>-2</sup>g/mL for MLC and 4.66×10<sup>-2</sup>g/mL for DLC, the inhibition effects of the as-prepared derivatives on the amyloid fibrillation of lysozyme (HEWL) were investigated detaily in water solution. 28915469 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Inhibition of Lysozyme Fibrillation by Gold Nanorods and Nanoparticles. 29442807 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE The data, altogether, suggest that the presence of ZnONP interface resulted in conformational rearrangements in the partially disordered lysozyme at pH 9.0 causing accumulation of non-amyloidogenic and functionally active intermediates, thus shielding the lysozyme from SDS induced fibrillation and cytotoxicity. 29778879 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE The prepared lysozyme amyloid fibrils as well as their mixtures with in-lab synthesized magnetic particles, which were prepared by adding the nanoparticles to the fibrils solution after the process of fibrillation was done, were characterized using brightfield trans-illumination-mode optical microscope, atomic force microscopy (AFM) and scanning electron microscope (SEM). 29128831 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Paclitaxel inhibited lysozyme fibrillation, and interacted with lysozyme through hydrogen bonds and van der Waals' interactions. 29352977 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Tannic Acid-Induced Surface-Catalyzed Secondary Nucleation during the Amyloid Fibrillation of Hen Egg-White Lysozyme. 30545098 2018
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Gallic acid induced dose dependent inhibition of lysozyme fibrillation. 28579468 2017
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Oxidized epigallocatechin gallate inhibited lysozyme fibrillation more strongly than the native form. 28038426 2017
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE The results also suggested that the differences in the initial protein conformation might alter the mechanism of fibrillation; however, at the higher protein concentrations lysozyme shifted to nucleation-dependent pathway. 28448956 2017
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE At low heparin concentrations, initial hen egg white lysozyme cluster formation and subsequent fibrillation is promoted by counter ion binding and screening of repulsive charges. 29101231 2017
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Our in vitro and cell culture results establish the ability of calnuc to inhibit fibrillation of insulin and lysozyme and validate its neuroprotective role in cells treated with amyloid fibrils. 27997158 2017
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE This work investigates the effect of the fibrillation and/or adsorption onto a layered double hydroxide material on the antibacterial properties of lysozyme. 28554056 2017
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE In addition, neither GO nor RGO induced the fibrillation of lysozyme after 12d incubation. 28324692 2017
CUI: C0232197
Disease: Fibrillation
Fibrillation
0.100 Biomarker disease BEFREE Amaranth delayed lysozyme fibrillation at 25 μM, while tartrazine had no effect even at 100 μM. 28094527 2017