MIR146A, microRNA 146a, 406938

N. diseases: 505; N. variants: 3
Disease: Idiopathic osteoarthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0409952
Disease: Idiopathic osteoarthritis
Idiopathic osteoarthritis 		0.010 Biomarker disease BEFREE Thus, miR-146a inhibits both OA and PTOA in mice, suggesting a common protective mechanism initiated by miR-146a. miR-146a suppresses IL-1β of catabolic factors, and we provide evidence that miR-146a directly inhibits Notch1 expression. 29575548 2018