MIR15A, microRNA 15a, 406948

N. diseases: 221; N. variants: 0
Disease: Childhood Osteosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.040 Biomarker disease BEFREE These findings indicated that miR‑15a may be a valuable target for the treatment of osteosarcoma, particularly for patients with high-grade cancer or heavy tumor burden. 29484432 2018
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.040 AlteredExpression disease BEFREE MiR-15a-3p was significantly downregulated in osteosarcoma cell lines and human osteosarcoma tumors. 28722268 2018
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.040 Biomarker disease BEFREE TNFAIP1 plays an important role in mediating miR-15a dependent biological functions in osteosarcoma. 26261520 2015
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.040 Biomarker disease BEFREE The data presented here demonstrate that the CCND1 contributes to osteosarcoma cell proliferation, suggesting that repression of CCND1 by miR-15a and miR-16-1 could be used for osteosarcoma therapy. 22922827 2012