MIR199A2, microRNA 199a-2, 406977

N. diseases: 87; N. variants: 1
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE Our results point to a novel role for miR-199a-3p and its downstream effector mTOR in human brown adipocyte differentiation and maintenance of thermogenic characteristics, which can be manipulated as therapeutic targets against obesity and its related metabolic disorders. 29753771 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.030 AlteredExpression disease BEFREE In the current study, we revealed that reduced expression of miR-199a-3p in adipose tissue resulting from high fat diet (HFD)-induced obesity in mice. 28803985 2017
CUI: C0028754
Disease: Obesity
Obesity 		0.030 Biomarker disease BEFREE FFA, TNF-α, IL‑6 and leptin significantly induced miR‑199a‑3p expression in mature human adipocytes, while resistin had the opposite effect. miR‑199a‑3p may represent a factor in the modulation of obesity‑associated IR and inflammatory responses. 27279151 2016