MIR200A, microRNA 200a, 406983

N. diseases: 156; N. variants: 0
Disease: Pterygium of eye ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4520843
Disease: Pterygium of eye
Pterygium of eye 		0.020 AlteredExpression disease BEFREE Expression of miR-200a in pterygium tissues was significantly lower than in conjunctiva controls (p = 0.015). 26995143 2016
CUI: C4520843
Disease: Pterygium of eye
Pterygium of eye 		0.020 AlteredExpression disease BEFREE The concerted down-regulation of four members from both clusters of the miR-200 family (miR-200a/-200b/-429 and miR-200c/-141), which are known to regulate EMT, and up-regulation of the predicted target and mesenchymal marker fibronectin (FN1), suggest that EMT could potentially play a role in the pathogenesis of pterygium and might constitute promising new targets for therapeutic intervention in pterygium. 23872359 2013