|
RETINAL DYSTROPHY AND IRIS COLOBOMA WITH OR WITHOUT CONGENITAL CATARACT
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma.
|
26056285 |
2015 |
|
RETINAL DYSTROPHY AND IRIS COLOBOMA WITH OR WITHOUT CONGENITAL CATARACT
|
0.700 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma.
|
26056285 |
2015 |
|
RETINAL DYSTROPHY AND IRIS COLOBOMA WITH OR WITHOUT CONGENITAL CATARACT
|
0.700 |
GermlineCausalMutation
|
disease |
ORPHANET |
microRNAs and inherited retinal dystrophies.
|
26159420 |
2015 |
|
RETINAL DYSTROPHY AND IRIS COLOBOMA WITH OR WITHOUT CONGENITAL CATARACT
|
0.700 |
GermlineCausalMutation
|
disease |
ORPHANET |
MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma.
|
26056285 |
2015 |
|
RETINAL DYSTROPHY AND IRIS COLOBOMA WITH OR WITHOUT CONGENITAL CATARACT
|
0.700 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
RETINAL DYSTROPHY AND IRIS COLOBOMA WITH OR WITHOUT CONGENITAL CATARACT
|
0.700 |
CausalMutation
|
disease |
CLINVAR |
|
|
|
|
Hepatitis B
|
0.320 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, we also showed that inhibition of Rab22a, one of the targets of miR-204, also suppressed intracellular and extracellular HBV DNA expression in HepG2.2.15.7 cells.
|
30042818 |
2018 |
|
Hepatitis B
|
0.320 |
Biomarker
|
disease |
CTD_human |
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
|
28545106 |
2017 |
|
Hepatitis B
|
0.320 |
Biomarker
|
disease |
BEFREE |
MicroRNA miR-204 and miR-1236 inhibit hepatitis B virus replication via two different mechanisms.
|
27734898 |
2016 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.310 |
Biomarker
|
disease |
BEFREE |
We further discovered that serum miR-204 was elevated in children and adults with T1D and in autoantibody-positive at-risk subjects but not in type 2 diabetes or other autoimmune diseases and was inversely correlated with remaining beta-cell function in recent-onset T1D.
|
31408375 |
2019 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.310 |
Biomarker
|
disease |
CTD_human |
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
|
28545106 |
2017 |
|
Pulmonary Hypertension
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Bromodomain-Containing Protein 4: The Epigenetic Origin of Pulmonary Arterial Hypertension.
|
26224795 |
2015 |
|
Malignant neoplasm of breast
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The results revealed that the expression of miR-204 was downregulated in all the tested breast cancer cell lines.
|
31424660 |
2020 |
|
Malignant Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Mechanistic investigation indicated that DLX6-AS1 acted as a cancer-promoting competing endogenous RNA (ceRNA) by binding miR-204-5p and upregulating OCT1.
|
31463827 |
2020 |
|
Neoplasm Metastasis
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The effect of miR-204 was evaluated on the breast cancer metastasis by cell migration and invasion transwell assays.
|
31424660 |
2020 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
These results indicated that miR-204-5p functions as a tumor suppressor by directly targeting IL-11 in ESCC.
|
31544245 |
2020 |
|
Breast Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The results revealed that the expression of miR-204 was downregulated in all the tested breast cancer cell lines.
|
31424660 |
2020 |
|
Tumor Cell Invasion
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The effect of miR-204 was evaluated on the breast cancer metastasis by cell migration and invasion transwell assays.
|
31424660 |
2020 |
|
Tumor Cell Invasion
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
In addition, the downregulated miRNA hsa-mir-204 promotes invasion and proliferation of gastric cancer cells by regulating the abnormal expression of mRNAs (CHRDL1 and NPTX1) and lncRNAs (ADAMTS9-AS2, NKX2-1-AS1, TLR8-AS1, and VCAN-AS1).
|
31452262 |
2020 |
|
Tumor Cell Invasion
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The research attempted to uncover the impacts of miR-204-3p on colon cancer cells growth, migration, and invasion. miR-204-3p expression level in colon cancer tissues and diverse colon cancer cell lines were testified by the quantitative real-time polymerase chain reaction.
|
31286521 |
2020 |
|
Primary malignant neoplasm
|
0.100 |
Biomarker
|
group |
BEFREE |
Mechanistic investigation indicated that DLX6-AS1 acted as a cancer-promoting competing endogenous RNA (ceRNA) by binding miR-204-5p and upregulating OCT1.
|
31463827 |
2020 |
|
Liver carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
LncRNA NEAT1 promotes autophagy via regulating miR-204/ATG3 and enhanced cell resistance to sorafenib in hepatocellular carcinoma.
|
31549407 |
2020 |
|
Malignant neoplasm of breast
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The outcome of the SMD from meta‑analysis also indicated that the expression of miR‑204‑5p was markedly reduced in 2,306 BC tissue samples in comparison to 367 para‑carcinoma tissue samples.
|
30569120 |
2019 |
|
Malignant neoplasm of breast
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Higher H19 (P = 0.001) along with lower miR-675 (P = 0.007) levels and higher miR-204 (P = 0.017) along with lower NEAT1 (P = 0.030) levels were detected in plasma of HER2-positive patients compared with the other BC subgroups.
|
30803129 |
2019 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
The expression of miR-204 was decreased, while AREG and p-AKT was increased in T3 stimulated BC cell lines.T3 stimulation promoted cell viability. miR-204 targets AREG to regulate its expression.
|
30406874 |
2019 |