MIR222, microRNA 222, 407007

N. diseases: 210; N. variants: 2
Disease: Gastritis, Atrophic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017154
Disease: Gastritis, Atrophic
Gastritis, Atrophic 		0.010 AlteredExpression disease BEFREE Gastrin increased miR-222 expression in AGSGR cells, with maximum changes observed at 10 nM G17 for 24 h. Signalling occurred via CCK2R and the PKC and PI3K pathways. miR-222 expression was increased in the serum and gastric corpus mucosa of hypergastrinemic INS-GAS mice and hypergastrinemic patients with autoimmune atrophic gastritis and type 1 gastric NETs; it decreased in patients following treatment with the CCK2R antagonist netazepide (YF476). 27323780 2016