Cervix carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Thus, PTX-miR-34a-MBs in combination with ultrasound microbubbles are a promising anticancer delivery strategy for treating cervical cancer.
|
31093891 |
2020 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This study provides insights into the roles of passenger strands (strand*) of the miR-34 family in cervical cancer.
|
30696040 |
2019 |
Cervix carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The low expression of miR-34a in patients with cervical cancer was correlated with the degree of tumor differentiation, lymph node metastasis and the International Federation of Gynecology and Obstetrics staging.
|
29456728 |
2018 |
Cervix carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Taken together, our findings indicate that the linc-UFC1 expression signature may serve as a novel biomarker for the diagnosis and prognosis of cervical cancer, and it is also highlighted that the E2F1-linc-UFC1/miR-34a/FOXP3 axis may be a potentially therapeutic target of cervical cancer.
|
29790665 |
2018 |
Cervix carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of MicroRNA-34a-5p Inhibits Proliferation and Promotes Apoptosis of Human Cervical Cancer Cells by Downregulation of Bcl-2.
|
28893346 |
2018 |
Cervix carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
MiR-21-5p upregulation, miR-34a downregulation, and hTERC amplification were associated with the aggressive progression of CC, which suggests that miR-21-5p, miR-34a and hTERC might serve as surrogate markers for CC progression and potential molecular targets for blockage of the development of CC.
|
29487007 |
2018 |
Cervix carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
All of these suggested that miR-34a and miR-206 might be the novel prognostic and therapy tools in cervical cancer.
|
28615991 |
2017 |
Cervix carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, the finding that the <i>CA9</i> SNP rs1048638 exerts its action through duplexes of the miR-34a and <i>CA9</i> 3'-UTRs and plays a vital role in cervical cancer in Taiwanese women may be applicable to translational medicine.
|
29100431 |
2017 |
Cervix carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
microRNA-34a-Upregulated Retinoic Acid-Inducible Gene-I Promotes Apoptosis and Delays Cell Cycle Transition in Cervical Cancer Cells.
|
26910120 |
2016 |
Cervix carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
This study confirmed a novel miR-34a-E2F3-survivin axis in the tumor suppressor role of miR-34a in cervical cancer.
|
25675046 |
2015 |
Cervix carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
MicroRNAs as biomarkers of cervical cancer development: a literature review on miR-125b and miR-34a.
|
24402874 |
2014 |
Cervix carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we sought to examine the hypothesis that neoadjuvant chemotherapy (NAC) is a better approach with improved prognosis and outcomes after laparoscopical radical hysterectomy (LRH) on patients with cervical cancer and to elucidate the potential roles of the p53:miR-34a:E2F1 and the p53:miR-605:Mdm2 signaling pathways in this therapy.
|
24335178 |
2013 |
Cervix carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We found that miR-34a is expressed at various levels in cervical cancer (HeLa, SiHa, C4I, C33a and CaSki) and trophoblast (BeWo and JAR) cell lines.
|
20351093 |
2010 |
Cervix carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
pri-miR-34a expression was significantly reduced in CIN and cervical cancer compared with normal cervical epithelium, as well as in CIN 2 and CIN 3 compared with CIN I.
|
20442590 |
2010 |