Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE MicroRNA-34a suppresses the invasion and migration of colorectal cancer cells by enhancing EGR1 and inhibiting vimentin. 31555358 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Expression of miR-34a-5p is up-regulated in human colorectal cancer and correlates with survival and clock gene PER2 expression. 31658284 2019
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE COUP‑TFII promotes epithelial‑mesenchymal transition by inhibiting miR‑34a expression in colorectal cancer. 30968145 2019
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE TGF-β secreted by tumor-associated macrophages promotes proliferation and invasion of colorectal cancer via miR-34a-VEGF axis. 30523755 2018
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression. 29970122 2018
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE miR-34a mediates oxaliplatin resistance of colorectal cancer cells by inhibiting macroautophagy <i>via</i> transforming growth factor-β/Smad4 pathway. 28348487 2017
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE MicroRNA-34a suppresses colorectal cancer metastasis by regulating Notch signaling. 28781671 2017
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer. 25712055 2015
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE MicroRNA-34a targets FMNL2 and E2F5 and suppresses the progression of colorectal cancer. 26103003 2015
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE miR-34a-5p suppresses colorectal cancer metastasis and predicts recurrence in patients with stage II/III colorectal cancer. 25362853 2015
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Dysregulation of microRNA-34a expression in colorectal cancer inhibits the phosphorylation of FAK via VEGF. 24370784 2014
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE Abnormal methylation of miR-34a and miR-34b/c genes might be regarded as potential biomarkers for noninvasive screening and diagnosis of colorectal cancer. 24573638 2014
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Although the biological relevance of nuclear GSK-3 level has not been fully studied, our results demonstrate that the tumor suppressor p53/miR-34 axis plays a role in regulating nuclear GSK-3 levels and Wnt signaling through the non-coding UTR of Axin2 in colorectal cancer. 23624843 2013
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression disease BEFREE Circulating miR-34a levels are reduced in colorectal cancer. 22648208 2012
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE MiR-34a (2.2-fold), miR-155 (2.3-fold) and miR-200c (3.1-fold) were all expressed at higher levels in colorectal cancer (P = 0.001, 0.005 and 0.001, respectively). 22562822 2012
Malignant neoplasm of colon and/or rectum
0.100 Biomarker disease BEFREE In the colorectal cancer samples a statistically significant correlation of miR-34a methylation and the absence of p53 mutation was detected. 21225432 2011