ARRB1, arrestin beta 1, 408

N. diseases: 92; N. variants: 3
Disease: Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.040 PosttranslationalModification disease BEFREE We also demonstrated that ARRB1 mediated prolonged phosphorylation of ERK1/2 and Akt in glioblastoma cells induced by NK1R activation. 28341744 2017
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.040 AlteredExpression disease BEFREE Downregulation of β-arrestin 1 suppresses glioblastoma cell malignant progression vis inhibition of Src signaling. 28442265 2017
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.040 AlteredExpression disease BEFREE Arrestin, Beta 1 (ARRB1), the host gene of miR-326, was also downregulated in GBM and interestingly, the expression of ARRB1 was also alleviated upon inhibition of the PI3 kinase pathway, indicating similar regulation pattern. 27871300 2016
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.040 Biomarker disease BEFREE These results suggest that beta-arrestin 1 dephosphorylation/inactivation is associated with aspects of the malignant behavior of glioblastomas. 19404096 2009