SMAD3, SMAD family member 3, 4088

N. diseases: 470; N. variants: 95
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
0.020 Biomarker phenotype BEFREE We present a case of EWSR1-SMAD3 positive fibroblastic tumor that occurred in a 24-year-old man who presented with a recurrent tumor in the dorsum of his right foot. 31376366 2019
CUI: C0521158
Disease: Recurrent tumor
Recurrent tumor
0.020 Biomarker phenotype BEFREE We propose that targeted blockade of the STAT3/SMAD3 axis in tumor cells may represent a novel therapeutic approach to prevent the plasticity required for metastatic progression and tumor recurrence. 28288136 2017