MAOA, monoamine oxidase A, 4128

N. diseases: 300; N. variants: 15
Disease: Panic Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 Biomarker disease BEFREE Does prior traumatization affect the treatment outcome of CBT for panic disorder? The potential role of the MAOA gene and depression symptoms. 28712090 2019
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 Biomarker disease BEFREE The present results support previous evidence for MAOA hypomethylation as a PD risk marker and suggest reversibility of MAOA hypomethylation as a potential epigenetic correlate of response to CBT. 27045843 2016
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 Biomarker disease BEFREE MAOA and mechanisms of panic disorder revisited: from bench to molecular psychotherapy. 23319006 2014
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 Biomarker disease BEFREE The present pilot data suggest a potential role of MAOA gene hypomethylation in the pathogenesis of panic disorder particularly in female patients, possibly mediating a detrimental influence of negative life events. 22436428 2012
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 GeneticVariation disease BEFREE Taken together, our meta-analysis therefore argues that high-expression MAOA-uVNTR alleles significantly increase the risk towards PD in women. 22911667 2012
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 AlteredExpression disease BEFREE With regard to the MAOA gene, a sequence variant that increases MAOA activity and has suggested association with the anxiety condition, panic disorder was preferentially transmitted from parents to affected children. 15523490 2005
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 GeneticVariation disease BEFREE This study was conducted to detect a possible association of a T941G single nucleotide polymorphism (SNP) in the monoamine oxidase A (MAOA) gene with generalized anxiety disorder (GAD), panic disorder (PD), or major depression (MD). 12555227 2003
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 GeneticVariation disease LHGDN Association of a MAOA gene variant with generalized anxiety disorder, but not with panic disorder or major depression. 12555227 2003
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 GeneticVariation disease BEFREE An analysis of possible synergistic effects of the MAO-A gene promoter variant and the short serotonin transporter (5-HTT) gene promoter variant in panic disorder was performed in a German and an Italian sample (combined panic disorder n = 144, combined controls n = 175). 12607224 2000
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 GeneticVariation disease LHGDN An analysis of possible synergistic effects of the MAO-A gene promoter variant and the short serotonin transporter (5-HTT) gene promoter variant in panic disorder was performed in a German and an Italian sample (combined panic disorder n = 144, combined controls n = 175). 12607224 2000
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 GeneticVariation disease BEFREE Recently, a positive association between panic disorder and a novel functional repeat polymorphism in the MAO-A gene promoter, with the longer alleles being more active, was reported. 11121185 2000
CUI: C0030319
Disease: Panic Disorder
Panic Disorder 		0.100 Biomarker disease BEFREE Together with the observation that inhibition of monoamine oxidase A is clinically effective in the treatment of panic disorder these findings suggest that increased monoamine oxidase A activity is a risk factor for panic disorder in female patients. 10072430 1999