MAOA, monoamine oxidase A, 4128

N. diseases: 300; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0237123
Disease: Alcohol or Other Drugs use
Alcohol or Other Drugs use
0.030 Biomarker disease BEFREE Converging evidence points to the monoamine oxidase A (MAOA) gene as a moderator of the effects of lifetime stress on the initiation of substance use. 29952131 2019
CUI: C0237123
Disease: Alcohol or Other Drugs use
Alcohol or Other Drugs use
0.030 GeneticVariation disease BEFREE SA, not PA, was associated with hypermethylation of the MAOA first exon relative to no-abuse, and the association was robust to adjustment for psychoactive medication, alcohol and drug dependence, and current substance use. 29600412 2018
CUI: C0237123
Disease: Alcohol or Other Drugs use
Alcohol or Other Drugs use
0.030 Biomarker disease BEFREE The cladogram served as the framework for nested ANOVA and logit analyses of association between MAOA and indices of liability to SUD (diagnosis, age of onset, and a dimensional index of substance use related problems) in a sample of adult males of European ancestry. 14755456 2004