MB, myoglobin, 4151

N. diseases: 125; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE Considerable progress has been made in understanding the condition of AMI through ascertaining the role of biomarkers, such as myoglobin, cardiac troponin proteins (T and I), creatine kinase-MB, and fatty acid-binding protein (FABP). 31782481 2020
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE Myoglobin was tested as a model target, and the limit of detection was 5.47 ng/mL in 20% diluted serum samples, which satisfies the requirements for clinical monitoring of acute myocardial infarction. 30571083 2019
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE Early detection of cardiac troponin I (cTnI), B-type natriuretic peptide (BNP), and myoglobin (Myo) is essential for the diagnosis of acute myocardial infarction (AMI) and heart failure (HF). 30985109 2019
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE However, AMI diagnosis is reliable only at intermediate and later stages, with myocardial injury (> 6 h) and MI, based on the expression of specific cardiac biomarkers including troponin I or T (cTnI or cTnT), creatine kinase-MB (CK-MB), and myoglobin. 30685097 2019
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE Here we investigated products of complement activation, C3d and soluble C5b9 (sC5b9), as potential biomarkers for myocardial injury and inflammation, as well as serum cytokines (IL-6 and TNF-alpha), alpha-1-acid glycoprotein (AGP), and classical markers of myocardial necrosis (creatine kinase, creatine kinase-MB isoform, myoglobin and troponin-I) in a longitudinal study of patients with AMI (from admission, 6 h and 12 h post admission, and at discharge from hospital). 29908956 2018
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE Serum myoglobin is one of the earliest markers for the diagnosis of acute myocardial infarction. 30519882 2018
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE Electroanalysis of myoglobin (Mb) in 10 plasma samples of healthy donors (HDs) and 14 plasma samples of patients with acute myocardial infarction (AMI) was carried out with screen-printed electrodes modified first with multi-walled carbon nanotubes (MWCNT) and then with a molecularly imprinted polymer film (MIP), viz., myoglobin-imprinted electropolymerized poly(o-phenylenediamine). 28763782 2018
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 AlteredExpression disease BEFREE A multivariate regression model showed as predictors for AMI the variables ECG data by admittance at the emergency room, previous AMI history, levels of both Mgb at the third hour, and cTnI at the sixth hour after admission. 29607545 2018
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 GeneticVariation disease BEFREE After an acute myocardial infarction (AMI) event, several cardiac markers are released into the blood, the most common of which are troponin, creatine kinase MB, C-reactive protein, and myoglobin. 28281270 2017
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE The aim of this study was to establish a dual-label time-resolved fluorescence immunoassay (TRFIA) for the simultaneous determination of cardiac troponin T (cTnT) and myoglobin (MYO) for the early diagnosis of acute myocardial infarction. 27879408 2017
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 AlteredExpression disease BEFREE After adjusting for age, gender, Killip classes, prior myocardiac infarction history, myoglobin, LVEF (left ventricular ejection fraction), diabetes, hypertension, smoking and systolic blood pressure, miR133a had a significant association with the risk of events at 12 months (HR = 2.869, P = 0.024) and 24 months (HR = 3.936, P = 0.001).In patients undergoing coronary angiography, circulating miR-133a is upregulated in AMI patients, but it does not provide enough accuracy for clinical AMI diagnosis because it also rises in unstable angina patients. 27124025 2016
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 Biomarker disease BEFREE Myoglobin (Myo), which is one of the early markers to increase after acute myocardial infarction (AMI), plays a major role in urgent diagnosis of cardiovascular diseases. 25216451 2015
CUI: C0155626
Disease: Acute myocardial infarction
Acute myocardial infarction
0.100 GeneticVariation disease BEFREE The objective of our study is to verify whether tumor necrosis factor-alpha -308 polymorphism is associated with risk of acute myocardial infarction (STEMI and NSTEMI) or with biochemical myocardial ischemia markers, such as troponin I, creatine kinase-MB, lactate dehydrogenase and myoglobin. 16319659 2005