MC4R, melanocortin 4 receptor, 4160

N. diseases: 149; N. variants: 58
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1391732
Disease: Cancer cachexia
Cancer cachexia
0.020 GeneticVariation disease BEFREE Previous evidence in animal models implicates the melanocortin-4 receptor gene (MC4R) in the development of cancer cachexia. 18377640 2008
CUI: C1391732
Disease: Cancer cachexia
Cancer cachexia
0.020 Biomarker disease BEFREE The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule melanocortin-4 receptor antagonist. 15774557 2005