MC4R, melanocortin 4 receptor, 4160

N. diseases: 149; N. variants: 58
Disease: Overweight and obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1561826
Disease: Overweight and obesity
Overweight and obesity 		0.030 GeneticVariation disease BEFREE Also, SNPs in LRRN6C (rs10968576) and MC4R (rs17782313) were significantly associated with overweight and obesity categories, respectively. 27486100 2016
CUI: C1561826
Disease: Overweight and obesity
Overweight and obesity 		0.030 GeneticVariation disease BEFREE Several studies have shown Single Nucleotide Polymorphisms (SNPs) linked to overweight and obesity, such as: rs1121980 (T/C) and rs9939609 (A/T) in Fat Mass and Obesity Associated gene (FTO) and rs17782313 (T/C) in Melanocortin 4 Receptor gene (MC4R). 24091943 2013
CUI: C1561826
Disease: Overweight and obesity
Overweight and obesity 		0.030 GeneticVariation disease BEFREE Val103Ile polymorphism of melanocortin-4 receptor is unlikely to be a major cause of overweight and obesity in Vojvodina, but further studies on larger groups of patients are needed. 19283510 2010