MDM4, MDM4 regulator of p53, 4194

N. diseases: 265; N. variants: 9
Disease: Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.030 AlteredExpression group BEFREE Overexpression of Mdm4 in mice drives the spontaneous development of mostly lymphomas and sarcomas. 27925213 2017
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.030 Biomarker group BEFREE These mice had significantly accelerated tumorigenesis and a distinct tumor spectrum with more carcinomas and significantly fewer lymphomas than p53(+/-) or Mdm4(Tg1) mice. 20736370 2010
CUI: C0024299
Disease: Lymphoma
Lymphoma 		0.030 AlteredExpression group BEFREE In acute- and lymphoma-type ATL, high expression of MRP1 mRNA at diagnosis correlated with shorter survival, and Cox regression analysis revealed that MRP1 expression was an independent prognostic factor. 11595704 2001