MDM4, MDM4 regulator of p53, 4194

N. diseases: 265; N. variants: 9
Disease: Multiple Myeloma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.040 Biomarker disease BEFREE Diffuse large B-cell lymphoma (DLBCL) and multiple myeloma (MM) cells infected by EBV display drug resistance-related proteins (MDR1, MRP1 and MRP2) and stem cell markers (OCT4 and SOX2). 28339079 2017
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.040 AlteredExpression disease BEFREE CD40 stimulation induces vincristine resistance via AKT activation and MRP1 expression in a human multiple myeloma cell line. 22445357 2012
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.040 AlteredExpression disease BEFREE The low activity of MDR- 1 and MRP-1 in MM need further clarification, indicating the involvement of different transport in the resistance mechanism. 15739024 2005
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.040 Biomarker disease BEFREE MDR1, MRP1 and LRP have been identified as important adverse prognostic factors in AML, T-ALL and MM. 10809991 2000