Disease: Amyloidosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002726
Disease: Amyloidosis
Amyloidosis 		0.030 AlteredExpression disease BEFREE In addition, fasudil reversed Aβ<sub>1-42</sub>-induced decreased expression of Bcl-2 and increases in caspase-3, cleaved-PARP, phospho-JNK(Thr183/Tyr185), and phospho-ASK1(Ser966). 31482248 2019
CUI: C0002726
Disease: Amyloidosis
Amyloidosis 		0.030 Biomarker disease BEFREE This ASK1 activation strongly correlated with islet amyloidosis and diabetes progression. 29627323 2018
CUI: C0002726
Disease: Amyloidosis
Amyloidosis 		0.030 Biomarker disease BEFREE Our results emphasize the importance of Ask1 cascade in Aβ toxicity, and of ERα and Ask1 as targets for developing new neuroprotective drugs. 22119000 2012