Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1112160
Disease: Gastrooesophageal cancer
Gastrooesophageal cancer
0.040 Biomarker disease BEFREE The aim of the work was to exploit a MET-amplified patient-derived xenograft model to optimize anti-MET therapeutic strategies in gastroesophageal cancer. 27524418 2017
CUI: C1112160
Disease: Gastrooesophageal cancer
Gastrooesophageal cancer
0.040 Biomarker disease BEFREE We also discuss the considerations and challenges for HGF/MET inhibitor drug development in the GEC setting. 24930887 2014
CUI: C1112160
Disease: Gastrooesophageal cancer
Gastrooesophageal cancer
0.040 Biomarker disease BEFREE We examined a GEC cohort with follow-up and reported the clinical response of four additional patients with MET-amplified tumors to the small molecule inhibitor crizotinib as part of an expanded phase I cohort study. 22042947 2011
CUI: C1112160
Disease: Gastrooesophageal cancer
Gastrooesophageal cancer
0.040 Biomarker disease BEFREE Therefore, the role of RON in gastroesophageal cancer, as well as its role in cooperative signaling with MET and as a mechanism of resistance to MET inhibition, was studied in gastroesophageal tissues and cell lines. 21543897 2011