MMP1, matrix metallopeptidase 1, 4312

N. diseases: 589; N. variants: 19
Disease: Prostate carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.090 GeneticVariation disease BEFREE Meta-analysis showed no associations between MMP1 rs1799750, MMP2 rs243865, or MMP7 rs11568818 and prostate cancer risk overall. 30464622 2018
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.090 GeneticVariation disease BEFREE Our findings suggest that the polymorphic genotypes at MMP-1 promoter -1607 may play a major role in determining personal cancer susceptibility for prostate cancer in Taiwan. 29970511 2018
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.090 Biomarker disease BEFREE The miR-124-prolyl hydroxylase P4HA1-MMP1 axis plays a critical role in prostate cancer progression. 25115393 2014
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.090 AlteredExpression disease BEFREE RhoB enhances migration and MMP1 expression of prostate cancer DU145. 19782069 2010
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.090 AlteredExpression disease BEFREE Furthermore, AI, retention allele of the MMP-1 promoter, and MMP-1 protein expression were analyzed in 77 prostate cancer specimens. 19639194 2009
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.090 GeneticVariation disease BEFREE For the MMP1 gene the polymorphic allele was more common in the control group than in the prostate cancer group (p <0.001). 19303106 2009
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.090 GeneticVariation disease BEFREE The 2G allele of the MMP-1 promoter polymorphism might not modify the risk of prostate cancer development and might not be used as a putative marker to predict the potential of metastasis in this cancer type, at least in the Turkish population. 18025848 2007
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.090 AlteredExpression disease BEFREE Whereas MMP-1 was overexpressed in NAP epithelial glands and progressively decreased from PIN to CaP, MMP-7, MMP-9 and MT1-MMP were more strongly expressed in CaP than in PIN and NAP tissue. 16619495 2006
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.090 AlteredExpression disease BEFREE Regulation of MMP-1 and MMP-13 expression may offer important therapeutic options for treating patients with prostate cancer. 12664060 2003