MMP2, matrix metallopeptidase 2, 4313

N. diseases: 1021; N. variants: 43
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.100 AlteredExpression disease BEFREE Here, we report ARHGAP4 as a new regulator of the β-catenin pathway that regulates cell invasion and migration of pancreatic cancer as well as the downstream effector MMP2 and MMP9 expression in vitro. 30958531 2019
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.100 AlteredExpression disease BEFREE Activation of pancreatic stellate cells may promote the expression of MMP2 and enhance the invasion and metastasis of pancreatic carcinoma. 30466735 2019
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.100 Biomarker disease BEFREE Our study demonstrates that the YY1/FER/STAT3/MMP2 axis is associated with the progression of pancreatic cancer and may provide a new therapeutic target for the treatment of pancreatic cancer. 31404611 2019
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.100 Biomarker disease BEFREE The anti-invasive effect of CL for BxPC-3 cells was found to occur through the inhibition of MMP2, MMP9, and MMP14. 30803757 2019
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma
0.100 Biomarker disease BEFREE The expressions of SMYD3, caspase-3, and matrix metallopeptidase-2 (MMP-2) were detected in pancreatic cancer and non-tumor tissues by immunohistochemistry. 31441002 2020