MMP3, matrix metallopeptidase 3, 4314

N. diseases: 473; N. variants: 24
Disease: Varicosity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042345
Disease: Varicosity
Varicosity 		0.030 AlteredExpression disease BEFREE Matrix metalloproteinases (MMPs), including MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9, and tissue inhibitor of metalloproteinase (TIMP) 1 and TIMP-3 are upregulated in varicose veins. 19847861 2009
CUI: C0042345
Disease: Varicosity
Varicosity 		0.030 GeneticVariation disease BEFREE The MMP1-1607dupG and MMP3-1171dupA promoter polymorphisms are not valuable markers of susceptibility for varicose veins. 19508478 2009
CUI: C0042345
Disease: Varicosity
Varicosity 		0.030 Biomarker disease BEFREE Fibronectin, a potential substrate of MMP3, was decreased in SMC from varicose veins. 16088212 2005