MMP9, matrix metallopeptidase 9, 4318

N. diseases: 1337; N. variants: 31
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013537
Disease: Eclampsia
Eclampsia
0.030 AlteredExpression disease BEFREE This study aims to investigate the molecular mechanism of how UCA1 interferes with MMP9 expression under the influence of metformin, which contributes to the development of pre-eclampsia. 31582211 2019
CUI: C0013537
Disease: Eclampsia
Eclampsia
0.030 Biomarker disease BEFREE To investigate the role of MMP-9 (-1562 C:T) polymorphism as a biomarker for susceptibility to pre-eclampsia. 23387490 2013
CUI: C0013537
Disease: Eclampsia
Eclampsia
0.030 GeneticVariation disease BEFREE While the TLR-2 +2258 (G>A) and MMP-9 -1562 (C>T) SNPs failed to present any significant association with pre-eclampsia, there was a marked trend for an association between the IL-4 -590 (C>T) SNP and pre-eclampsia (chi(2)= 5.87, P = 0.055), with a prevalence of TT homozygous women in this group (OR 4.455, 95% CI 1.286-15.350). 18651887 2008