MMP9, matrix metallopeptidase 9, 4318

N. diseases: 1337; N. variants: 31
Disease: Chagas Disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041234
Disease: Chagas Disease
Chagas Disease 		0.040 Biomarker disease BEFREE We have pointed out that MMP-2 and MMP-9 together can predict clinical evolution in Chagas disease. 31578449 2019
CUI: C0041234
Disease: Chagas Disease
Chagas Disease 		0.040 AlteredExpression disease BEFREE On the other hand, T. cruzi derived-antigens promote a differential expression of MMP-2 and MMP-9 in patients with Chagas disease and may regulate MMPs expression in neutrophils and monocytes, mainly when a cardiac alteration is not present. 28118356 2017
CUI: C0041234
Disease: Chagas Disease
Chagas Disease 		0.040 Biomarker disease BEFREE Here, we consolidate all characteristics involving MMP-2 and MMP-9 in Chagas' disease based on current studies to clarify their participation on the inflammation/regulation and fibrosis, and the synergistic or antagonistic role between them. 28543409 2017
CUI: C0041234
Disease: Chagas Disease
Chagas Disease 		0.040 Biomarker disease BEFREE While MMP-9 seems to be involved in the inflammation and cardiac remodeling of Chagas disease, MMP-2 does not correlate with inflammatory molecules. 23856618 2013