MMP9, matrix metallopeptidase 9, 4318

N. diseases: 1337; N. variants: 31
Disease: early pregnancy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0747845
Disease: early pregnancy
early pregnancy 		0.020 AlteredExpression phenotype BEFREE The KLF8 levels, MMP-9 levels, and trophoblast invasion were similarly altered; the levels peaked at 8 to 10 weeks of gestation and declined thereafter along with oxygen tension increased from hypoxia to normoxia during early pregnancy, decreased in third trimester placentas from PE pregnancies featured by repeated H/R and HTR8/SVneo cells exposed to H/R compared with the control. 23703536 2014
CUI: C0747845
Disease: early pregnancy
early pregnancy 		0.020 GeneticVariation phenotype BEFREE Functional SNP -1562C/T in the promoter region of MMP9 and recurrent early pregnancy loss. 22118839 2012