MMP12, matrix metallopeptidase 12, 4321

N. diseases: 216; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 AlteredExpression disease BEFREE Moreover, Spearman's rank correlation test showed a significant inverse correlation between the percentage of MMP12-positive cells and increased levels of ETC-expressing areas in EMPD and SCC (r = -.5997). 31264287 2019
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 Biomarker disease BEFREE Differential expression of matrilysin-1 (MMP-7), 92 kD gelatinase (MMP-9), and metalloelastase (MMP-12) in oral verrucous and squamous cell cancer. 14694517 2004
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 AlteredExpression disease BEFREE By in situ hybridization, expression of MMP-12 mRNA was detected in 28/33 vulvar SCC samples in CD-68-positive macrophages, while 10 samples had positive cancer cells. 12237887 2002
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.040 Biomarker disease BEFREE Human macrophage metalloelastase was detected in 11 of 17 squamous cell carcinomas in epithelial cancer cells, whereas macrophages were positive in 15 of 17 samples. 10844553 2000