MPO, myeloperoxidase, 4353

N. diseases: 653; N. variants: 25
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.350 AlteredExpression disease BEFREE These animals showed an inverse association of the severity of HCC with bioactive hepcidin levels, which was significantly correlated with the hepatic myeloperoxidase activity. 30774778 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.350 GeneticVariation disease BEFREE A variant in myeloperoxidase promoter hastens the emergence of hepatocellular carcinoma in patients with HCV-related cirrhosis. 21907168 2012
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.350 Biomarker disease BEFREE These findings suggest MPO levels monitoring may be a potential biological marker to HCC screening in patients with HCV. 22985908 2012
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.350 GeneticVariation disease BEFREE Both the 2G-myeloperoxidase genotype and carriage of one or two copies of the Ala-superoxide dismutase 2 allele were more frequent in patients with cirrhosis or HCC. 20673159 2011
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.350 GeneticVariation disease BEFREE The GG-MPO genotype did not modify iron but increased the risks of HCC and death. 19731237 2009
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.350 Biomarker disease CTD_human Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis. 19731237 2009