MSX2, msh homeobox 2, 4488

N. diseases: 135; N. variants: 7
Disease: Amputated structure (morphologic abnormality) ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0332840
Disease: Amputated structure (morphologic abnormality)
Amputated structure (morphologic abnormality) 		0.010 Biomarker phenotype BEFREE We transduced mBMSCs with <i>Msx1</i> and <i>Msx2</i> genes and compared osteogenic activity and expression levels of several <i>Msx</i>-regulated genes (<i>Bmp4</i>, <i>Fgf8</i>, and keratin 14 (<i>K14</i>)) in BlC groups, including MSX1, MSX2, and MSX1/2 (in a 1:1 ratio) with those in mBMSCs and BCs <i>in vitro</i> and <i>in vivo</i> following injection into the amputation site. 28461333 2017