COX1, cytochrome c oxidase subunit I, 4512

N. diseases: 421; N. variants: 89
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis
0.020 Biomarker disease BEFREE However, the inhibition of COX-1 in cells of the gastrointestinal (GI) system and COX-2 in vascular cells translates into increased risk of serious GI adverse events and atherothrombosis and hypertension, respectively. 23953622 2014
CUI: C1963943
Disease: Atherothrombosis
Atherothrombosis
0.020 Biomarker disease BEFREE Whereas the role of platelet COX-1 in acute ischemic diseases is established, the role of COX-2 in atherothrombosis remains unclear. 16785826 2006